Takako Fujiwara Selected Research

OPC 28326

7/2015

OPC-28326, a selective peripheral vasodilator with angiogenic activity, mitigates postinfarction cardiac remodeling.

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Takako Fujiwara Research Topics

Disease

27	Myocardial Infarction 01/2018 - 10/2002
21	Infarction (Infarctions) 01/2018 - 10/2002
13	Heart Failure 01/2020 - 09/2004
13	Fibrosis (Cirrhosis) 03/2012 - 05/2005
13	Ischemia 04/2011 - 10/2002
7	Cardiomyopathies (Cardiomyopathy) 01/2019 - 01/2006
6	Hypertrophy 03/2012 - 07/2005
5	Cicatrix (Scar) 03/2009 - 06/2004
4	Inflammation (Inflammations) 03/2012 - 09/2006
4	Ventricular Remodeling 10/2007 - 05/2003
3	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 01/2020 - 02/2003
3	Hypoxia (Hypoxemia) 07/2015 - 08/2010
3	Starvation 12/2012 - 05/2009
3	Emphysema 01/2012 - 10/2006
3	Cardiomegaly (Heart Hypertrophy) 07/2011 - 02/2003
3	Coronary Occlusion 06/2010 - 06/2004
3	Reperfusion Injury 06/2010 - 12/2007
3	Diabetic Nephropathies (Diabetic Nephropathy) 11/2008 - 08/2005
3	Atrophy 02/2008 - 01/2006
2	Heart Diseases (Heart Disease) 09/2019 - 02/2003
2	Cardiotoxicity 12/2012 - 02/2010
2	Pneumonia (Pneumonitis) 01/2012 - 01/2007
2	Pulmonary Emphysema 01/2012 - 10/2006
2	Diabetes Mellitus 01/2012 - 05/2009
2	Peripheral Arterial Disease 04/2011 - 06/2009
2	Anemia 11/2010 - 08/2010
2	Myocardial Ischemia (Ischemic Heart Diseases) 12/2009 - 12/2007
2	Type 2 Diabetes Mellitus (MODY) 07/2009 - 09/2002
2	Coronary Artery Disease (Coronary Atherosclerosis) 05/2009 - 04/2005
1	Lysosomal Storage Diseases (Lysosomal Storage Disease) 09/2017
1	Glycogen Storage Disease Type II (Pompe's Disease) 09/2017
1	Colitis 05/2014

Drug/Important Bio-Agent (IBA)

9	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2019 - 01/2006
9	Adenosine Triphosphate (ATP)IBA 12/2012 - 10/2002
9	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 04/2011 - 06/2004
8	Erythropoietin FDA Link 04/2013 - 01/2006
6	Proteins (Proteins, Gene)FDA Link 05/2014 - 09/2002
5	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 05/2014 - 05/2003
4	Amino Acids FDA Link 09/2019 - 05/2009
4	Indicators and Reagents (Reagents)IBA 01/2018 - 04/2007
4	Green Fluorescent ProteinsIBA 12/2012 - 02/2004
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 04/2013 - 12/2009
3	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 12/2012 - 05/2009
3	Superoxides (Superoxide)IBA 01/2012 - 04/2007
3	Pancreatic Elastase (Elastase)IBA 01/2012 - 10/2006
3	GelatinIBA 04/2011 - 09/2008
3	HydrogelsIBA 04/2011 - 09/2008
3	Nitric Oxide Synthase (NO Synthase)IBA 06/2010 - 04/2007
3	Fas Ligand Protein (Fas Ligand)IBA 02/2010 - 09/2004
3	Hydroxyl RadicalIBA 07/2009 - 10/2007
3	CytokinesIBA 03/2009 - 02/2006
3	Protein Kinase CIBA 10/2007 - 10/2002
2	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 11/2010
2	Fluorouracil (Carac)FDA LinkGeneric 01/2019 - 06/2005
2	Pharmaceutical PreparationsIBA 01/2019 - 05/2009
2	ResveratrolIBA 01/2018 - 03/2013
2	Therapeutic UsesIBA 05/2014 - 07/2005
2	Cathepsin DIBA 12/2012 - 05/2009
2	asialoerythropoietinIBA 03/2012 - 11/2010
2	bafilomycin A1IBA 06/2011 - 05/2009
2	Erythropoietin Receptors (Erythropoietin Receptor)IBA 11/2010 - 01/2006
2	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 08/2010 - 06/2010
2	Hypoglycemic Agents (Hypoglycemics)IBA 06/2010 - 05/2009
2	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 12/2009 - 03/2009
2	2,5-dihydroxybenzoic acid (gentisic acid)IBA 07/2009 - 12/2007
2	KATP ChannelsIBA 07/2009 - 10/2002
2	Evans Blue (Blue, Evans)FDA Link 05/2009 - 04/2007
2	mitochondrial K(ATP) channelIBA 05/2009 - 04/2007
2	Coloring Agents (Dyes)IBA 05/2009 - 04/2007
2	Transforming Growth Factor beta (TGF-beta)IBA 11/2008 - 05/2005
2	Glucose (Dextrose)FDA LinkGeneric 11/2008 - 10/2008
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2007 - 04/2007
2	DesminIBA 05/2007 - 01/2006
2	Troponin IIBA 05/2007 - 01/2006
2	Myosin Heavy Chains (Myosin Heavy Chain)IBA 05/2007 - 01/2006
2	5-hydroxydecanoic acidIBA 04/2007 - 10/2002
2	Heparin-binding EGF-like Growth Factor (HB-EGF)IBA 06/2006 - 07/2005
2	Norepinephrine (Noradrenaline)FDA LinkGeneric 04/2005 - 01/2003
2	Matrix Metalloproteinases (MMPs)IBA 06/2004 - 02/2004
2	LipidsIBA 06/2002 - 05/2002
1	5-Methylcytosine (5 Methylcytosine)IBA 01/2020
1	GlycogenIBA 09/2017
1	LipofuscinIBA 09/2017
1	pimonidazoleIBA 07/2015
1	OPC 28326IBA 07/2015
1	sodium sulfate (sodium bisulfate)FDA LinkGeneric 05/2014
1	Dextrans (Dextran)FDA Link 05/2014
1	Sialyl Lewis X AntigenIBA 04/2013
1	Liposomes (Liposome)IBA 04/2013
1	Chloroquine (Aralen)FDA LinkGeneric 03/2013

Therapy/Procedure

8	Therapeutics 01/2018 - 02/2004
6	Ligation 05/2014 - 02/2003
3	Transplantation 10/2006 - 02/2006
2	Intramuscular Injections 05/2014 - 02/2010
2	Intraperitoneal Injections 12/2012 - 01/2006
2	Microspheres (Microsphere) 04/2011 - 06/2009
2	Nephrectomy 11/2010 - 03/2007
1	Drug Therapy (Chemotherapy) 01/2019
1	Caloric Restriction 01/2018
1	Immunomodulation 05/2014